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Sensors for Single-Use Bioreactors

Posted in Life Sciences on Thursday, August 22nd, 2019. No comments yet
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For pharmaceutical and biopharmaceutical manufacturers, scaling up production has typically meant large, 5000+ liter stainless steel bioreactors for the process. These require cleaning and sterilization between batches. Market demands are driving the need for more flexibility with smaller batches. Single-use technologies (SUT) are being applied to bioreactors to address these demands and reduce the cost […]

Optimizing Biomanufacturing in Real Time

Posted in Life Sciences on Wednesday, April 24th, 2019. No comments yet
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One of the inherent challenges in top-down scheduling systems, such as manufacturing plans generated from Enterprise Resource Planning (ERP) systems (Level 4 in ANSI/ISA-95 model), are that they are typically based on the ideal state of manufacturers’ processes. The real state may quite different and include issues with equipment, processing steps that didn’t go as […]

Taming Big Data in the Life Sciences

Posted in Life Sciences on Wednesday, April 3rd, 2019. No comments yet
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The Interphex conference for pharmaceutical and biotech manufacturers is underway this week in New York City. Emerson’s Bob Lenich is presenting Big Data in Life Sciences Manufacturing. Bob opens citing one pharmaceutical manufacturer who generates 5000 data points every second during a production run. This data rate translates into 1.3*1010 pieces of data per production […]

BioPhorum Roadmap for In-line Monitoring and Real-time Release

Posted in Life Sciences on Monday, April 1st, 2019. No comments yet
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Professionals across the Life Sciences industry are gathering this week in New York City for Interphex. Organizers bill this conference as: …the premier pharmaceutical, biotechnology, and device development and manufacturing event where you can “Experience Science through Commercialization”. Emerson’s Michalle Adkins will be presenting, Update on BioPhorum’s Roadmap for In-line Monitoring and Real- Time Release […]

Advancing Digital Plant Maturity for Biopharmaceutical Manufacturers

Posted in Life Sciences on Thursday, March 28th, 2019. No comments yet
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At the recent 2019 China International Biopharma4.0 Summit, Emerson’s Ron Rossbach presented Biopharma 4.0—Integrated Software Enabling Digital Capabilities. I’ll highlight some of Ron’s key points. He opened describing some of the main challenges biopharmaceutical manufacturers seek to address through enterprise digitalization—reducing time to market, increasing capital expenditure (CAPEX) productivity, increasing operational efficiency and improving forecasting […]