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Archive for the ‘Life Sciences’ Category

Predictive and Prescriptive Maintenance in Life Sciences

Posted in Life Sciences, Reliability on Friday, January 17th, 2020. No comments yet
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When you think of machinery for industrial use, often images of refineries, oil & gas production sites and other visual images come to mind. But what about the machinery and other equipment in industries with shiny stainless steel everywhere, such as pharmaceutical, biotech and food & beverage manufacturing? The pumps, fans, and other pieces of […]

Innovating to Meet Bioprocessing Single-Use Requirements

Posted in Analyzers, Life Sciences on Friday, October 25th, 2019. No comments yet
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Manufacturing in the biotech industry has been undergoing many changes. An ADC Review article, Emerging Trends in Single-Use Technology in the Manufacturing of Antibody-Drug Conjugates, highlighted one of these trends: First introduced in the late 1970s in the form of disposable capsules and a range of filters, single-use technologies were revolutionized in the late 2000s […]

Biomanufacturing Fluidic System Single-Use Technologies

Posted in Fluid and Motion Control, Life Sciences on Wednesday, October 9th, 2019. No comments yet
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As medicines and therapies become more specialized for individuals, the requirements of biopharmaceutical manufacturing processes are dramatically changing, especially in the transition from large-scale to single-use production processes. In a Processing magazine article, Process Control Automation Systems Maximize Biomanufacturing Agility in Single-Use Applications, Emerson’s Mukta Sharma highlights important technologies for single-use production processes. Mukta opens […]

Sensors for Single-Use Bioreactors

Posted in Life Sciences on Thursday, August 22nd, 2019. No comments yet
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For pharmaceutical and biopharmaceutical manufacturers, scaling up production has typically meant large, 5000+ liter stainless steel bioreactors for the process. These require cleaning and sterilization between batches. Market demands are driving the need for more flexibility with smaller batches. Single-use technologies (SUT) are being applied to bioreactors to address these demands and reduce the cost […]

Optimizing Biomanufacturing in Real Time

Posted in Life Sciences on Wednesday, April 24th, 2019. No comments yet
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One of the inherent challenges in top-down scheduling systems, such as manufacturing plans generated from Enterprise Resource Planning (ERP) systems (Level 4 in ANSI/ISA-95 model), are that they are typically based on the ideal state of manufacturers’ processes. The real state may quite different and include issues with equipment, processing steps that didn’t go as […]