Posts Tagged ‘ISA-88’

Designing and Building Pharmaceutical and Biotech Smart Factories

Posted in Life Sciences, Operations Management on Wednesday, February 7th, 2018. No comments yet
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Pharmaceutical and biotech manufacturers seek to improve both project and operational performance through implementation of smart factory technology. The smart factory fits right into the S95 enterprise automation model and provides out-of-box manufacturing functionality representing the best practice in the industry and complying with the regulation such as cGMP. The smart factory technology connects the […]

Challenge of Designing PCS-Driven MES Architectures for a Greenfield Facility

Posted in Life Sciences, Operations Management on Monday, April 24th, 2017. No comments yet
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Author: Jonathan Lustri I have previously written about a design strategy where the process control system (PCS) is the primary system driving all procedural batch activity within a pharmaceutical process. In this architecture, the PCS ISA-88 procedural model must execute the both automated procedures and call the manufacturing execution system (MES) workflows to be executed […]

Optimizing Batch Process Automation Design in MES and DCS

Posted in Life Sciences, Operations Management on Tuesday, October 27th, 2015. 2 comments so far
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For pharmaceutical and biotech manufacturers, the flow and capture of information is as important as the flow of the manufacturing process in readying products to release for sale. In a Pharmaceutical Technology magazine article, Connecting MES to Process Control, Emerson’s Jonathan Lustri is interviewed about advances in using the ISA-88 standard to coordinate manufacturing execution […]

Improving Technology Transfer by Earlier Adoption of Standards and Software Platforms

Posted in Life Sciences, Operations Management on Thursday, August 21st, 2014. 2 comments so far
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In 2011, the U.S. Food & Drug Administration (FDA) published their Guidance for Industry – Process Validation: General Principles and Practices. A PharmManufacturing.com article, A Framework for Technology Transfer to Satisfy the Requirements of the New Process Validation Guidance: Part 2 shared the impact on the Life Sciences industry: In the life of any drug […]

Applying Batch Analytics to Fermentation Processes

Posted in Data Management on Tuesday, March 6th, 2012. 2 comments so far
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Creating batch process models such as fermentation is challenging due to their inherent time variability batch to batch. It’s also critical to know when problems are beginning to develop when corrective measures can be taken. Emerson’s David Rehbein, a Senior Data Management Solutions consultant, recently gave an IFPAC presentation, Batch Analytics Applied to a Fermentation […]

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