Greg describes the book Biochemical Measurement and Control:
When Monsanto was making the transition to a life science company, I had the opportunity to work on fermenter measurement and control for various genetically engineered products. Important opportunities identified then such as the application of mass spectrometers, dissolved carbon dioxide probes, and inferential measurements of metabolic processes have come to fruition today opening the door to more advanced process analysis and control techniques. Additionally the applications gave me a chance to apply my expertise in pH measurement and control in new ways and dig into the practical aspects of dissolved oxygen measurement and control.
As he goes on to mention, the progression of technology and new thinking prompted an updated version, New Directions in Bioprocess Modeling and Control: Maximizing Process Analytical Technology Benefits published by ISA in 2006. This book:
…provides an updated view and details on new tools for batch modeling, analysis, and control. This ISA book includes the development of neural network inferential measurements of dryer moisture by Washington University in Saint Louis and my first principle dynamic fermentor models for the National Corn to Ethanol Research Center. The book concludes with an excellent review of new technology for batch analytics by the University of Texas.
As I had mentioned in an earlier post, Greg has chosen to make many of his works available as free eBooks once the copyrights are returned to him. So, for the next many years, the Bioprocess book is available for purchase from the ISA folks or in the DeltaV Bookstore, along with many other great books we’ve discovered along the way.
We live in great times where many with expertise make it freely available. If this expertise happens to intersect with our interests and we have some bandwidth to absorb it, we’re but a mere Google search (or whatever your favorite search engine happens to be) away. It just wasn’t this easy way back when!