Posts Tagged ‘manufacturing execution system’

Tracking Cell Therapy Chain of Identity

Posted in Life Sciences, Operations Management on Monday, November 5th, 2018. No comments yet
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Cell therapy is when: …cellular material is injected into a patient;[1] this generally means intact, living cells. For example, T cells capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy. For manufacturers in the Life Sciences industry, making these therapies poses challenges since each batch is specific to […]

Best Practices for Implementing a Process Control Driven MES System

Posted in Life Sciences, Operations Management on Tuesday, August 21st, 2018. No comments yet
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Author: Jonathan Lustri I have previously been interviewed and written about a process control and MES [Manufacturing Execution Systems] architecture where the batch control logic within the process control system is the single procedural engine. It drives procedural logic and workflows executed by the MES system when called by the process control system. The benefit […]

Moving to Electronic Batch Records

Posted in Life Sciences, Operations Management on Wednesday, May 30th, 2018. One comment so far
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Yesterday we highlighted advancements in exception management technology for pharmaceutical and biopharmaceutical manufacturers. Exception management is one element in an electronic batch record (EBR). Other elements for the EBR which also have high data integrity requirements include equipment management, material management and batch record process flow and recipe management. In a PharmTech article, Making the […]

Improving Batch Manufacturing Quality Review Cycle Time

Posted in Life Sciences, Operations Management on Tuesday, May 29th, 2018. One comment so far
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Exceptions in batch manufacturing processes are the deviations that occur outside the prescribed specifications. For pharmaceutical and biopharmaceutical manufacturers, quality and manufacturing personnel must review these exceptions. Traditionally, this quality review process occurs after the batch has completed. A recent news release, Emerson Helps Life Sciences Companies Reduce Time to Market with Faster Quality Reviews, […]

Tech Transfer in Drug Development Pipeline and Industry 4.0

Posted in Life Sciences on Tuesday, May 22nd, 2018. No comments yet
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Author: Zuwei Jin Among all of the important trends in life sciences industry such as modular plants, integrated modules, out-of-box smart factory, single-use equipment, PAT, and manufacturing execution systems (MES), IIOT has been receiving high interest including among pharmaceutical and biotech manufacturers. It is our view that the same technology advancement that makes Industry 4.0 […]