Manufacturing in the biotech industry has been undergoing many changes. An ADC Review article, Emerging Trends in Single-Use Technology in the Manufacturing of Antibody-Drug Conjugates, highlighted one of these trends: First introduced in the late 1970s in the form of disposable capsules and a range of filters, single-use technologies were revolutionized in the late 2000s […]
Digital twins provide a simulation of the manufacturing or production process as well as the automation systems which control it. Depending on the level of fidelity of the process models, this digital twin can have many uses. I caught up with Emerson’s Zuwei Jin who shared some of his thoughts around these digital twins. He […]
For pharmaceutical and biopharmaceutical manufacturers, scaling up production has typically meant large, 5000+ liter stainless steel bioreactors for the process. These require cleaning and sterilization between batches. Market demands are driving the need for more flexibility with smaller batches. Single-use technologies (SUT) are being applied to bioreactors to address these demands and reduce the cost […]
The Interphex conference for pharmaceutical and biotech manufacturers is underway this week in New York City. Emerson’s Bob Lenich is presenting Big Data in Life Sciences Manufacturing. Bob opens citing one pharmaceutical manufacturer who generates 5000 data points every second during a production run. This data rate translates into 1.3*1010 pieces of data per production […]
The U.S. Food & Drug Administration (FDA) outlines the drug development process in five steps: Discovery and development Preclinical research Clinical trials FDA review FDA post-market safety monitoring I caught up with Emerson’s Zuwei Jin whom you may recall from earlier posts on the role of automation in the drug development process. Zuwei explained to […]
Powered by WordPress