In BioPhorum’s MES of the Future Manifesto, Sean and Kate Porter collaborated with other biomanufacturing leaders on requirements for future Manufacturing Execution Systems.
BioPhorum MES of the Future
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pharmaceutical manufacturing
Hygienic Pressure Measurement for Pharmaceutical and Bioprocess Applications
In a Process Instrumentation article, How to ensure reliable pressure transmitter measurement in pharmaceutical applications, Emerson’s Brandon Haschke shares how “Advanced hygienic pressure transmitters can reduce downtime and operating costs thanks to long-term stability that requires fewer calibrations.”
Overcoming Pharmaceutical and Biotech Manufacturing Challenges
Emerson’s Christian Berg presented Are We There Yet? Tackling Manufacturing Challenges with the Digital Plant at the Pharma Manufacturing World Summit in Boston.
Adaptable Landscape Components Facilitate Digital Transformation
The BioPhorum Operations Group (BPOG) established a digital plant maturity model (DPMM) for biopharmaceutical manufacturing to define stages of factory evolution “from simple paper-based plants through to the fully automated and integrated ‘adaptive plant’ of the future.” The model gives organizations a common tool for industry comparison and measurement of progress. It also provides a platform to facilitate collaboration within the life sciences industry and its technology providers.
Increasing Life Sciences Manufacturing Capacity
In an Australasian BioTechnology article, Facilities for a Strong Future, Emerson’s Michalle Adkins and Makarand Mujumdar share how pharmaceutical and biotech manufacturers can improve local capacity to meet the needs of the regions in which they operate.
Four Pillars for Life Sciences Line and Facility Efficiency
There are four core pillars we look to address in order to support pharmaceutical and biopharmaceutical manufacturers in achieving line and facility efficiency goals.
Improving Equipment Reliability for Life Sciences Manufacturers
Reliability of assets used in the manufacturing process is paramount for safe, efficient and effective operations. Unplanned asset failures, improper asset performance, poor maintenance planning, and untimely follow-through can cause shutdowns, under-utilized production equipment, deviations, or material/product losses.
Holistic Production Readiness Strategy is Key to Operational Success
Initiating Good Manufacturing Practices (GMP) production operations, whether as part of facility start-up, product changeover, or following a shutdown, requires complex coordination of both logical and physical process controls. Inefficient configuration and qualification practices for automation and information management systems can lead to both start-up delays and productivity losses.
Real-time Scheduling and Capacity Analysis Address Manufacturing Challenges
Neo Chow Yang shares how Emerson’s Real-Time Modeling System allows users to visualize the facility constraints, accommodate variability, maximize production, and understand the implications of any change in the manufacturing process.
Avoiding Unplanned Downtime in Life Sciences Industry
For manufacturers in the Life Sciences industry, production challenges often occur in these four areas—production readiness, equipment reliability, personnel effectiveness and facility/line efficiency. In this post, I’ll focus on equipment reliability, and specifically, unplanned downtime.
Improve the Flow, then Automate
Flow is the foundation of world class production processes. Impediments to flow result in waste (transportation, inventory, motion, waiting, over-processing, over-production, defects). Unfortunately, digital solutions are often leveraged to address observed wastes in production processes without first addressing foundational problems.
Fast Tracking Adaptable Manufacturing in Life Sciences
In a presentation at the ACHEMA Pulse virtual conference this year, Emerson’s Alan Johnston shared how fast rollout of COVID vaccine manufacturing has changed the mindset of how quickly a new therapy can move from development to commercial manufacturing and ultimately to the consumer.
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The opinions expressed here are the personal opinions of the authors. Content published here is not read or approved by Emerson before it is posted and does not necessarily represent the views and opinions of Emerson.